Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model

Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model

Abstract Background The emergence of multidrug-resistant strains of Plasmodium falciparum poses a great threat of increased fatalities in cases of cerebral and other forms of severe malaria infections in which parenteral artesunate monotherapy is the current drug of choice. The study aimed to invest...

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Bibliographic Details
Main Authors: Onyango C. Odhiambo, Hannah N. Wamakima, Gabriel N. Magoma, Peter G. Kirira, Bonface J. Malala, Francis T. Kimani, Francis W. Muregi
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Malaria Journal
Subjects:
Covalent bitherapy
Polypharmacology
Trioxaquine
Cerebral malaria
Online Access:http://link.springer.com/article/10.1186/s12936-017-1917-6

Internet

http://link.springer.com/article/10.1186/s12936-017-1917-6

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