Expression and Function of Transmembrane-4 Superfamily (Tetraspanin) Proteins in Osteoclasts: Reciprocal Roles of Tspan-5 and NET-6 during Osteoclastogenesis
Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system. Recent studies have revealed that a family of tetraspanin proteins, such...
Main Authors: | Kaori Iwai, Masaru Ishii, Shiro Ohshima, Kunio Miyatake, Yukihiko Saeki |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-01-01
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Series: | Allergology International |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015308959 |
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