CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5+

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5+

Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal tissues is presented, in part, as suppressed hippocampal neurogenesis and impaired cognitive f...

Full description

Bibliographic Details
Main Authors: David Leu, Ivan Spasojevic, Huy Nguyen, Brian Deng, Artak Tovmasyan, Tin Weitner, Romulo S. Sampaio, Ines Batinic-Haberle, Ting-Ting Huang
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717300721

Internet

http://www.sciencedirect.com/science/article/pii/S2213231717300721

Similar Items