Caveolae couple mechanical stress to integrin recycling and activation

Cells are subjected to multiple mechanical inputs throughout their lives. Their ability to detect these environmental cues is called mechanosensing, a process in which integrins play an important role. During cellular mechanosensing, plasma membrane (PM) tension is adjusted to mechanical stress thro...

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Bibliographic Details
Main Authors: Fidel-Nicolás Lolo, Dácil María Pavón, Araceli Grande-García, Alberto Elosegui-Artola, Valeria Inés Segatori, Sara Sánchez, Xavier Trepat, Pere Roca-Cusachs, Miguel A del Pozo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/82348