Caveolae couple mechanical stress to integrin recycling and activation
Cells are subjected to multiple mechanical inputs throughout their lives. Their ability to detect these environmental cues is called mechanosensing, a process in which integrins play an important role. During cellular mechanosensing, plasma membrane (PM) tension is adjusted to mechanical stress thro...
Main Authors: | Fidel-Nicolás Lolo, Dácil María Pavón, Araceli Grande-García, Alberto Elosegui-Artola, Valeria Inés Segatori, Sara Sánchez, Xavier Trepat, Pere Roca-Cusachs, Miguel A del Pozo |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-10-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/82348 |
Similar Items
-
IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover
by: Katerina M. Vakaloglou, et al.
Published: (2016-03-01) -
Integrin Adhesion Complex Organization in Sheep Myometrium Reflects Changing Mechanical Forces during Pregnancy and Postpartum
by: Bryan A. McLendon, et al.
Published: (2021-06-01) -
Mechanical communication-associated cell directional migration and branching connections mediated by calcium channels, integrin β1, and N-cadherin
by: Mingxing Ouyang, et al.
Published: (2022-08-01) -
Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates
by: Ivana Samaržija, et al.
Published: (2020-07-01) -
Editorial: Integrin adhesion receptors in health and disease
by: Vassiliki Kostourou, et al.
Published: (2023-02-01)