Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatment.

Many heme enzymes show remarkable versatility and atypical kinetics. The fungal extracellular enzyme chloroperoxidase (CPO) characterizes a variety of one and two electron redox reactions in the presence of hydroperoxides. A structural counterpart, found in mammalian microsomal cytochrome P450 (CYP)...

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Bibliographic Details
Main Authors: Kelath Murali Manoj, Arun Baburaj, Binoy Ephraim, Febin Pappachan, Pravitha Parapurathu Maviliparambathu, Umesh K Vijayan, Sivaprasad Valiyaveettil Narayanan, Kalaiselvi Periasamy, Ebi Ashley George, Lazar T Mathew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2871781?pdf=render