QbD Consideration for Developing a Double-Layered Tablet into a Single-Layered Tablet with Telmisartan and Amlodipine

The aim of this study was to develop a single-layered version of commercially available Twynstar<sup>®</sup> (Telmisartan + Amlodipine) double-layered tablets to improve the dosing convenience. A quality-by-design approach was applied to develop the single-layered version. To evaluate th...

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Bibliographic Details
Main Authors: Joo-Eun Kim, Young-Joon Park
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/2/377