Antibiotic use and the efficacy of immune checkpoint inhibitors in cancer patients: a pooled analysis of 2740 cancer patients

Antibiotic use and the efficacy of immune checkpoint inhibitors in cancer patients: a pooled analysis of 2740 cancer patients

The gut microbiota plays a critical role in the anti-tumor immune response. There is increasing data showing that antibiotics (ATBs) change the composition of the gut microbiota and affect the efficacy of immune checkpoint inhibitors (ICIs). However, this is the first meta-analysis to evaluate the a...

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Bibliographic Details
Main Authors: Xuan-Zhang Huang, Peng Gao, Yong-Xi Song, Yan Xu, Jing-Xu Sun, Xiao-Wan Chen, Jun-Hua Zhao, Zhen-Ning Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:OncoImmunology
Subjects:
antibiotics
immune checkpoint inhibitors
immunotherapy
overall survival
progression-free survival
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1665973

Internet

http://dx.doi.org/10.1080/2162402X.2019.1665973

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