Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules

Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules

The search for novel anti-cancer compounds which can circumvent chemotherapeutic drug resistance and limit systemic toxicity remains a priority. 2-Ethyl-3-<i>O</i>-sulphamoyl-estra-1,3,5(10)15-tetraene-3-ol-17one (ESE-15-one) and 2-ethyl-3-<i>O</i>-sulphamoyl-estra-1,3,5(10)1...

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Bibliographic Details
Main Authors: Anne E. Mercier, Renaud Prudent, Michael S. Pepper, Leanne De Koning, Elsie Nolte, Lauralie Peronne, Marcel Nel, Laurence Lafanechère, Anna M. Joubert
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
microtubules
reactive oxygen species
apoptosis
autophagy
2-methoxyestradiol analogues
anti-cancer
Online Access:https://www.mdpi.com/1420-3049/26/3/706

Internet

https://www.mdpi.com/1420-3049/26/3/706

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