Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

Abstract Background Hydroquinone (HQ) is a phenolic metabolite of benzene with a potential risk for hematological disorders and hematotoxicity in humans. In the present study, an integrative analysis of microRNA (miRNA) and mRNA expressions was performed to identify potential pathways and miRNA-mRNA...

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Bibliographic Details
Main Authors: Chun-Hong Yu, Shui-Qing Yang, Lei Li, Yu Xin, Fang Zhang, Xiao-Fan Liu, Zong-Chun Yi
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-022-00556-8