Modulating asthma–COPD overlap responses with IL-17 inhibition

Modulating asthma–COPD overlap responses with IL-17 inhibition

BackgroundIL-17 is a modulator of the inflammatory response and is implicated in lung remodeling in both asthma and chronic obstructive pulmonary disease (COPD). Well as and probably in patients with asthma–COPD overlap (ACO).MethodsIn this study, we evaluated the response of the airways and alveola...

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Main Authors: Leandro do Nascimento Camargo, Renato Fraga Righetti, Francine Maria de Almeida, Tabata Maruyama dos Santos, Silvia Fukuzaki, Nilo Arthur Bezerra Martins, Miguel Cantadori Barbeiro, Beatriz Mangueira Saraiva-Romanholo, Fernanda Degobbi Tenorio Quirino dos Santos Lopes, Edna Aparecida Leick, Carla Máximo Prado, Iolanda de Fátima Lopes Calvo Tibério
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
asthma
asthma-COPD overlap (ACO)
inflammation
anti-IL-17
extracellular matrix remodeling
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271342/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271342/full

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