Phenylalanine Stereoisomers of CJ-15,208 and [<span style="font-variant: small-caps">d</span>-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

Phenylalanine Stereoisomers of CJ-15,208 and [<span style="font-variant: small-caps">d</span>-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

The macrocyclic tetrapeptide <i>cyclo</i>[Phe-<span style="font-variant: small-caps;">d</span>-Pro-Phe-Trp] (CJ-15,208) and its stereoisomer <i>cyclo</i>[Phe-<span style="font-variant: small-caps;">d</span>-Pro-Phe-<span style=&q...

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Bibliographic Details
Main Authors: Ariana C. Brice-Tutt, Sanjeewa N. Senadheera, Michelle L. Ganno, Shainnel O. Eans, Tanvir Khaliq, Thomas F. Murray, Jay P. McLaughlin, Jane V. Aldrich
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
opioid peptide
macrocyclic tetrapeptide
multifunctional ligands
structure-activity relationships
kappa opioid receptor
delta opioid receptor
Online Access:https://www.mdpi.com/1420-3049/25/17/3999

Internet

https://www.mdpi.com/1420-3049/25/17/3999

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