Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen

Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen

The objective of this study was to synthesize seven novel thiourea derivatives of naproxen (<b>8</b>–<b>14</b>), examine the anti-inflammatory activity of the newly synthesized compounds, investigate the cytotoxic potential of both sets of synthesized compounds (<b>1<...

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Bibliographic Details
Main Authors: Nikola Nedeljković, Miloš Nikolić, Petar Čanović, Milan Zarić, Radica Živković Zarić, Jelena Bošković, Marina Vesović, Jovana Bradić, Marijana Anđić, Aleksandar Kočović, Marina Nikolić, Vladimir Jakovljević, Zorica Vujić, Vladimir Dobričić
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
naproxen
thiourea
anti-inflammatory activity
paw edema
cytotoxic activity
MTT
Online Access:https://www.mdpi.com/1999-4923/16/1/1

Internet

https://www.mdpi.com/1999-4923/16/1/1

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