Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice
Loss of dysferlin (DYSF) protein in humans results in limb-girdle muscular dystrophy 2B, characterized by progressive loss of muscles in the distal limbs with impaired locomotion. The DYSF-null (Bla/J) mouse develops severe steatotic muscles upon aging. Here, we report a marked increase in adipocyte...
Auteurs principaux: | , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Elsevier
2019-12-01
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Collection: | Journal of Lipid Research |
Sujets: | |
Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S0022227520310440 |