Growth capacity of a Wharton’s Jelly derived mesenchymal stromal cells tissue engineered vascular graft used for main pulmonary artery reconstruction in piglets

Growth capacity of a Wharton’s Jelly derived mesenchymal stromal cells tissue engineered vascular graft used for main pulmonary artery reconstruction in piglets

Background: Surgical treatment of congenital heart defects affecting the right ventricular outflow tract (RVOT) often requires complex reconstruction and multiple reoperations due to structural degeneration and lack of growth of currently available materials. Hence, alternative approaches for RVOT r...

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Bibliographic Details
Main Authors: Dominga Iacobazzi, Mohamed T. Ghorbel, Filippo Rapetto, Srinivas A. Narayan, Julia Deutsch, Tasneem Salih, Amy G. Harris, Katie L. Skeffington, Richard Parry, Giulia Parolari, Guillaume Chanoit, Massimo Caputo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
right ventricular outflow tract reconstruction
tissue engineering
small intestinal submucosa
growing swine model
preclinical efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1360221/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2024.1360221/full

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