Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells

Aquaporin-2 (AQP2) is a molecular water channel protein responsible for water reabsorption by the kidney collecting ducts. Many water balance disorders are associated with defects in AQP2 gene expression regulated by the peptide hormone vasopressin. Here, we studied roles of Elf3 (E26 transformation...

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Main Authors: Shu-Ting Lin, Chia-Ching Ma, Kuang-Ting Kuo, Yin-Fang Su, Wei-Ling Wang, Tzu-Hsien Chan, Shih-Han Su, Shih-Che Weng, Chian-Huei Yang, Shuei-Liong Lin, Ming-Jiun Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01308/full