Deregulation of phytoene-β-carotene synthase results in derepression of astaxanthin synthesis at high glucose concentration in Phaffia rhodozyma astaxanthin-overproducing strain MK19

Deregulation of phytoene-β-carotene synthase results in derepression of astaxanthin synthesis at high glucose concentration in Phaffia rhodozyma astaxanthin-overproducing strain MK19

Abstract Background A major obstacle to industrial-scale astaxanthin production by the yeast Phaffia rhodozyma is the strong inhibitory effect of high glucose concentration on astaxanthin synthesis. We investigated, for the first time, the mechanism of the regulatory effect of high glucose (> 100...

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Bibliographic Details
Main Authors: Lili Miao, Shuang Chi, Mengru Wu, Zhipei Liu, Ying Li
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Microbiology
Subjects:
Phaffia rhodozyma
Glucose metabolism
Astaxanthin
Phytoene-β-carotene synthase
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12866-019-1507-6

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http://link.springer.com/article/10.1186/s12866-019-1507-6

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