Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity

Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity

Background & Aims: Histological assessment of liver biopsies is the gold standard for diagnosis of non-alcoholic steatohepatitis (NASH), the progressive form of non-alcoholic fatty liver disease (NAFLD), despite its well-established limitations. Therefore, non-invasive biomarkers that can of...

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Bibliographic Details
Main Authors: Frederik T. Larsen, Daniel Hansen, Mike K. Terkelsen, Sofie M. Bendixen, Fabio Avolio, Charlotte W. Wernberg, Mette M. Lauridsen, Lea L. Grønkjaer, Birgitte G. Jacobsen, Ellen G. Klinggaard, Susanne Mandrup, Tina Di Caterino, Majken S. Siersbæk, Vineesh Indira Chandran, Jonas H. Graversen, Aleksander Krag, Lars Grøntved, Kim Ravnskjaer
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:JHEP Reports
Subjects:
NAFLD
NASH
SMOC2
non-invasive biomarker
hepatic stellate cells
transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555922001872

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http://www.sciencedirect.com/science/article/pii/S2589555922001872

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