TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination
Abstract The newborn immune system is characterized by diminished immune responses that leave infants vulnerable to virus-mediated disease and make vaccination more challenging. Optimal vaccination strategies for influenza A virus (IAV) in newborns should result in robust levels of protective antibo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-022-00523-8 |