The Binding Properties of Antibodies to Z-DNA in the Sera of Normal Healthy Subjects

Antibodies to DNA are a diverse set of antibodies that bind sites on DNA, a polymeric macromolecule that displays various conformations. In a previous study, we showed that sera of normal healthy subjects (NHS) contain IgG antibodies to Z-DNA, a left-handed helix with a zig-zig backbone. Recent stud...

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Bibliographic Details
Main Authors: David S. Pisetsky, Matthew J. Gedye, Lawrence A. David, Diane M. Spencer
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/5/2556