Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection

Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection

Interleukin-1 alpha (IL-1α) and interleukin-1 beta (IL-1β) are pro-inflammatory cytokines that are induced after Cryptococcus neoformans infection and activate the interleukin-1 receptor type I (IL-1RI). To establish the role of IL-1RI signaling in protection against cryptococcal infection, we analy...

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Bibliographic Details
Main Authors: Mitra Shourian, Ben Ralph, Isabelle Angers, Donald C. Sheppard, Salman T. Qureshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Cryptococcus neoformans
fungal pneumonia
interleukin-1
interleukin-1 receptor
lung inflammation
cytokines
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01987/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01987/full

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