Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents

BackgroundTreatment stratification and response assessment in pediatric sarcomas has relied on imaging studies and surgical/histopathological evidence of vital tumor cells. Such studies and evidence collection processes often involve radiation and/or general anesthesia in children. Cell-free circula...

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Bibliographic Details
Main Authors: Markus G. Seidel, Karl Kashofer, Tina Moser, Andrea Thueringer, Bernadette Liegl-Atzwanger, Andreas Leithner, Joanna Szkandera, Martin Benesch, Amin El-Heliebi, Ellen Heitzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.926405/full