Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant

Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant

Abstract The destruction of the pulmonary epithelial barrier in acute respiratory distress syndrome is caused by the damage of the alveolar epithelial cells. Oroxin A is an effective flavonoid component derived from the medicinal plant Oroxylum indicum (L.) Kurz. In this study, the oleic acid (OA)-i...

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Bibliographic Details
Main Authors: JIAN HUANG, CHEN CHEN, JIANQIN XIE, KERONG ZHAI, SHILIN WEI, XINGDONG CHENG, RONGZHI ZHANG
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2022-12-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Oroxin A
oleic acid
surfactant protein C
pyroptosis
ARDS
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000800601&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000800601&tlng=en

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