Screening and Carrier Rate of Neuronal Ceroid Lipofuscinosis in Chihuahua Dogs in Japan

Screening and Carrier Rate of Neuronal Ceroid Lipofuscinosis in Chihuahua Dogs in Japan

Neuronal ceroid lipofuscinosis (NCL) is a group of rare lethal neurodegenerative lysosomal storage diseases that occur in a range of dog breeds, including Chihuahuas. Recently, a homozygous single base-pair deletion (c.846delT), which causes a frame shift generating a premature stop codon (p.Phe282L...

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Bibliographic Details
Main Authors: Shahnaj Pervin, Md Shafiqul Islam, Naomi Tada, Toshihiko Tsutsui, Mohammad Mahbubur Rahman, Akira Yabuki, Martia Rani Tacharina, Tofazzal Md Rakib, Shinichiro Maki, Osamu Yamato
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Animals
Subjects:
carrier rate
Chihuahua dog
<i>CLN7</i>/<i>MFSD8</i> gene
neuronal ceroid lipofuscinosis
real-time PCR assay
Online Access:https://www.mdpi.com/2076-2615/12/9/1210

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https://www.mdpi.com/2076-2615/12/9/1210

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