Stage-specific adhesion of Leishmania promastigotes to sand fly midguts assessed using an improved comparative binding assay.

The binding of Leishmania promastigotes to the midgut epithelium is regarded as an essential part of the life-cycle in the sand fly vector, enabling the parasites to persist beyond the initial blood meal phase and establish the infection. However, the precise nature of the promastigote stage(s) that...

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Bibliographic Details
Main Authors: Raymond Wilson, Michelle D Bates, Anna Dostalova, Lucie Jecna, Rod J Dillon, Petr Volf, Paul A Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2935393?pdf=render