Single-molecule three-color FRET with both negligible spectral overlap and long observation time.

Single-molecule three-color FRET with both negligible spectral overlap and long observation time.

Full understanding of complex biological interactions frequently requires multi-color detection capability in doing single-molecule fluorescence resonance energy transfer (FRET) experiments. Existing single-molecule three-color FRET techniques, however, suffer from severe photobleaching of Alexa 488...

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Bibliographic Details
Main Authors: Sanghwa Lee, Jinwoo Lee, Sungchul Hohng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2924373?pdf=render

Internet

http://europepmc.org/articles/PMC2924373?pdf=render

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