Folic acid-modified reverse micelle-lipid nanocapsules overcome intestinal barriers and improve the oral delivery of peptides

Folic acid-modified reverse micelle-lipid nanocapsules overcome intestinal barriers and improve the oral delivery of peptides

AbstractThe oral absorption of exenatide, a type 2 diabetes medication, can be increased by employing lipid nanocapsules (LNC). To increase mucus permeability and exenatide intestinal absorption, reverse micelle lipid nanocapsules (RM-LNC) were prepared and their surface was modified with DSPE-PEG-F...

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Bibliographic Details
Main Authors: Jibiao He, Ruihuan Ding, Yuping Tao, Zhenyu Zhao, Ranran Yuan, Houqian Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Folic acid
targeted drug delivery
lipid nanocapsules
oral administration
reverse micelle
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2023.2181744

Internet

https://www.tandfonline.com/doi/10.1080/10717544.2023.2181744

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