Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells

Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells

Abstract Background Indigofera suffruticosa Mill. is used as a folk medicine for treating patients with leukemia, however very little is known regarding the molecular mechanism of its anti-leukemic activity and the chemical profile of the active extract. The present study aimed to reveal the molecul...

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Bibliographic Details
Main Authors: Hong-Loan Tran, Kuei-Hung Lai, Hsun-Shuo Chang, Yi-Siao Chen, Hui-Chun Wang, Shuen-Shin Yang, Hsueh-Wei Chang, Chin-Mu Hsu, Chia-Hung Yen, Hui-Hua Hsiao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Folk medicine
Indigofera suffruticosa
Acute lymphoblastic leukemia
Online Access:https://doi.org/10.1186/s12906-023-04325-w

Internet

https://doi.org/10.1186/s12906-023-04325-w

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