Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast
<p>Abstract</p> <p>Background</p> <p><it>N</it>-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties. The systems prote...
Main Authors: | , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
BMC
2005-06-01
|
叢編: | BMC Genetics |
在線閱讀: | http://www.biomedcentral.com/1471-2156/6/31 |