Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been reported: the balance among disease resolution, an a...

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Bibliographic Details
Main Authors: Zahra Khalajzeyqami, Andrea Grandi, Erica Ferrini, Francesca Ravanetti, Ludovica Leo, Martina Mambrini, Luciana Giardino, Gino Villetti, Franco Fabio Stellari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200302/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200302/?tool=EBI

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