Loop Entropy Assists Tertiary Order: Loopy Stabilization of Stacking Motifs

Loop Entropy Assists Tertiary Order: Loopy Stabilization of Stacking Motifs

The free energy of an RNA fold is a combination of favorable base pairing and stacking interactions competing with entropic costs of forming loops. Here we show how loop entropy, surprisingly, can promote tertiary order. A general formula for the free energy of forming multibranch and other RNA loop...

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Bibliographic Details
Main Author: Daniel P. Aalberts
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Entropy
Subjects:
RNA
coaxial stacking
tertiary structure
secondary structure
multibranch loops
Hairpin loops
polymer simulations
Online Access:http://www.mdpi.com/1099-4300/13/11/1958/

Internet

http://www.mdpi.com/1099-4300/13/11/1958/

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