Targeting OPA1-Mediated Mitochondrial Fusion Contributed to Celastrol’s Anti-Tumor Angiogenesis Effect

Celastrol, an active triterpenoid extracted from one of the most famous traditional Chinese medicines (TCMs), <i>Tripterygium wilfordii</i> Hook.f., is a novel anti-cancer drug with significant anti-angiogenesis activity. However, the exact molecular mechanisms underlying its anti-tumor...

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Bibliographic Details
Main Authors: Gaofu Li, Lei Zhou, Huifang Deng, Congshu Huang, Ningning Wang, Lanxin Yue, Pengfei Zhang, Yongqiang Zhou, Wei Zhou, Yue Gao
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/1/48