Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitgation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia

Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitgation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia

Abstract Background Macrophage migration inhibitory factor (MIF) has been implicated as a protective factor in the development of bronchopulmonary dysplasia (BPD) and is known to be regulated by MicroRNA-451 (miR-451). The aim of this study was to evaluate the role of miR-451 and the MIF signaling p...

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Bibliographic Details
Main Authors: Margaret Gilfillan, Pragnya Das, Dilip Shah, Mohammad Afaque Alam, Vineet Bhandari
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Respiratory Research
Subjects:
miR-451
Hyperoxia
Alveolarization
Lung
Angiopoietin
Vascular endothelial growth factor
Online Access:http://link.springer.com/article/10.1186/s12931-020-01353-9

Internet

http://link.springer.com/article/10.1186/s12931-020-01353-9

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