Inflammasome activation: from molecular mechanisms to autoinflammation

Abstract Inflammasomes are assembled by innate immune sensors that cells employ to detect a range of danger signals and respond with pro‐inflammatory signalling. Inflammasomes activate inflammatory caspases, which trigger a cascade of molecular events with the potential to compromise cellular integr...

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Bibliographic Details
Main Authors: Samuel Lara‐Reyna, Emily A Caseley, Joanne Topping, François Rodrigues, Jorge Jimenez Macias, Sean E Lawler, Michael F McDermott
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1404