Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model

Abstract Background Osteoarthritis (OA), a degenerative disease with a high global prevalence, is characterized by the degradation of the extracellular matrix (ECM) and the apoptosis of chondrocytes. Ajugol, a extract derived from the herb Rehmannia glutinosa, has not yet been investigated for its p...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Jingtao Wu, Heng Yu, Yangcan Jin, Jingquan Wang, Liwen Zhou, Teng Cheng, Zhao Zhang, Binghao Lin, Jiansen Miao, Zhongke Lin
स्वरूप: लेख
भाषा:English
प्रकाशित: BMC 2023-09-01
श्रृंखला:Chinese Medicine
विषय:
ऑनलाइन पहुंच:https://doi.org/10.1186/s13020-023-00824-7