Reduced total serum bilirubin levels are associated with ulcerative colitis.

Chronic inflammation associated with inflammatory bowel disease (IBD) results in increased oxidative stress that damages the colonic microenvironment. Low levels of serum bilirubin, an endogenous antioxidant, have been associated with increased risk for Crohn's disease (CD). Therefore, the aim...

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Bibliographic Details
Main Authors: Kathleen M Schieffer, Shannon M Bruffy, Richard Rauscher, Walter A Koltun, Gregory S Yochum, Carla J Gallagher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0179267