NEK1 Variants in a Cohort of Italian Patients With Amyotrophic Lateral Sclerosis

NEK1 Variants in a Cohort of Italian Patients With Amyotrophic Lateral Sclerosis

IntroductionIn the last few years, different studies highlighted a significant enrichment of NEK1 loss of function (LoF) variants in amyotrophic lateral sclerosis (ALS), and an additional role for the p.Arg261His missense variant in the disease susceptibility. Several other missense variants have be...

Full description

Bibliographic Details
Main Authors: Nilo Riva, Laura Pozzi, Tommaso Russo, Giovanni Battista Pipitone, Paride Schito, Teuta Domi, Federica Agosta, Angelo Quattrini, Paola Carrera, Massimo Filippi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neuroscience
Subjects:
motor neuron disease
frontotemporal dementia
neuromuscular diseases
neurodegenerative disorders
genetics
never in mitosis a (NIMA)-related kinase 1
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.833051/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.833051/full

Similar Items