Management and prediction of immune-related adverse events for PD1/PDL-1 immunotherapy in colorectal cancer

Programmed cell death protein (PD-1) is an important immunosuppressive molecule, which can inhibit interaction between PD-1 and its ligand PD-L1, further enhancing the T cell response and anti-tumor activity, which is called immune checkpoint blockade. Immunotherapy, represented by immune checkpoint...

Full description

Bibliographic Details
Main Authors: Liting Sun, Cong Meng, Xiao Zhang, Jiale Gao, Pengyu Wei, Jie Zhang, Zhongtao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1167670/full