Screening of GHSR, GHRHR, GH1 genes in isolated growth hormone deficiency disease in Egyptian patients

Screening of GHSR, GHRHR, GH1 genes in isolated growth hormone deficiency disease in Egyptian patients

Abstract Background Isolated growth hormone deficiency (IGHD) is a hereditary disorder that causes significant short stature. GHD has a reported incidence of 1/4000–1/10,000 births. It is caused by mutations in the major somatotroph axis genes, involving GH1, codes for growth hormone, GHSR, and GHRH...

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Bibliographic Details
Main Authors: Tamer H. A. Ammar, Ghada M. M. Al-Ettribi, Maha M. A. Abo Hashish, Tarek M. Farid, Amany A. Abou-Elalla, Manal M. Thomas
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Growth hormone deficiency
GH1 gene
GHRHR gene
GHSR gene
Sanger sequencing analysis
Online Access:https://doi.org/10.1186/s43042-024-00480-y

Internet

https://doi.org/10.1186/s43042-024-00480-y

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