A small molecule inhibitor of leucine carboxyl methyltransferase-1 inhibits cancer cell survival

Reversible phosphorylation is the basis for signal transduction in eukaryotic cells, and this is tightly controlled by the complex interplay of kinases and phosphatases. Many malignancies are characterized by dysregulation of the delicate protein phosphorylation balance. The targeting of protein pho...

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Bibliographic Details
Main Authors: O. A. Arosarena, A. S. Saribas, E. P. Papadopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Drug Discovery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2024.1278163/full