Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes

Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes

During menopause, when estrogen levels are low, abnormalities in the hypothalamic preoptic area (POA) of the thermoregulatory center can cause hot flashes. However, the involved neural population has not been identified. Proteomics showed that under low estrogen, differentially expressed proteins in...

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Bibliographic Details
Main Authors: Yanrong Sun, Hanfei Wang, Wenjuan Wang, Jiali Lu, Jinglin Zhang, Xiaofeng Luo, Liju Luan, Ke Wang, Jing Jia, Junhao Yan, Lihua Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
hot flashes
glutamatergic neurons
GABAergic neurons
glutamate decarboxylase
thermosensitive transient receptor potentials
estrogen receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.993955/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.993955/full

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