Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment

Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment

Background & Aims: Pegylated interferon alpha (pegIFNα) is commonly used for the treatment of people infected with HDV. However, its mode of action in HDV-infected cells remains elusive and only a minority of people respond to pegIFNα therapy. Herein, we aimed to assess the responsiveness of...

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Bibliographic Details
Main Authors: Katja Giersch, Paulina Perez-Gonzalez, Lennart Hendricks, Nora Goldmann, Jonathan Kolbe, Lennart Hermanussen, Jan-Hendrick Bockmann, Tassilo Volz, Annika Volmari, Lena Allweiss, Joerg Petersen, Dieter Glebe, Marc Lütgehetmann, Maura Dandri
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:JHEP Reports
Subjects:
HDV
Human liver chimeric mice
Resistance
Antiviral
Genotype
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000046

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http://www.sciencedirect.com/science/article/pii/S2589555923000046

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