Fasting‐induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

Abstract Recent studies have demonstrated that repeated short‐term nutrient withdrawal (i.e. fasting) has pleiotropic actions to promote organismal health and longevity. Despite this, the molecular physiological mechanisms by which fasting is protective against metabolic disease are largely unknown....

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Main Authors: Jessica Fuhrmeister, Annika Zota, Tjeerd P Sijmonsma, Oksana Seibert, Şahika Cıngır, Kathrin Schmidt, Nicola Vallon, Roldan M de Guia, Katharina Niopek, Mauricio Berriel Diaz, Adriano Maida, Matthias Blüher, Jürgen G Okun, Stephan Herzig, Adam J Rose
Format: Article
Language:English
Published: Springer Nature 2016-05-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201505801