Design of Beta-2 Microglobulin Adsorbent Protein Nanoparticles

Design of Beta-2 Microglobulin Adsorbent Protein Nanoparticles

Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. B2M is naturally shed from cell surfaces into the plasma, followed by renal excretion. In patients with impaired renal function, B2M will accumulate in organs and tissues leading to sign...

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Bibliographic Details
Main Authors: Justin E. Miller, Roger Castells-Graells, Mark A. Arbing, Aldo Munoz, Yi-Xiao Jiang, Charlize T. Espinoza, Brian Nguyen, Paul Moroz, Todd O. Yeates
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomolecules
Subjects:
protein design
beta-2 microglobulin (B2M)
amyloidosis
dialysis
middle molecules
protein cages
Online Access:https://www.mdpi.com/2218-273X/13/7/1122

Internet

https://www.mdpi.com/2218-273X/13/7/1122

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