Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model

Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model

Post-traumatic spinal cord remodeling includes both degenerating and regenerating processes, which affect the potency of the functional recovery after spinal cord injury (SCI). Gene therapy for spinal cord injury is proposed as a promising therapeutic strategy to induce positive changes in remodelin...

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Bibliographic Details
Main Authors: Maria Aleksandrovna Davleeva, Ravil Rasimovich Garifulin, Farid Vagizovich Bashirov, Andrei Aleksandrovich Izmailov, Leniz Faritovich Nurullin, Ilnur Ildusovich Salafutdinov, Dilara Zilbarovna Gatina, Dmitrij Nikolaevich Shcherbinin, Andrei Aleksandrovich Lysenko, Irina Leonidovna Tutykhina, Maksim Mikhailovich Shmarov, Rustem Robertovich Islamov
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
autologous genetically-enriched leucoconcentrate; chimeric adenoviral vector; gene therapy; glial cell line‐derived neurotrophic factor; mini-pig; neural cell adhesion molecule; spinal cord contusion injury; vascular endothelial growth factor
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1505;epage=1511;aulast=Davleeva

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1505;epage=1511;aulast=Davleeva

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