Establishment and Characterization of Free-Floating 3D Macrophage Programming Model in the Presence of Cancer Cell Spheroids

Establishment and Characterization of Free-Floating 3D Macrophage Programming Model in the Presence of Cancer Cell Spheroids

Reprogramming of tumor-associated macrophages (TAMs) is a promising strategy for cancer immunotherapy. Several studies have shown that cancer cells induce/support the formation of immunosuppressive TAMs phenotypes. However, the specific factors that orchestrate this immunosuppressive process are unk...

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Bibliographic Details
Main Authors: Ksenija Korotkaja, Juris Jansons, Karina Spunde, Zhanna Rudevica, Anna Zajakina
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
macrophage plasticity
tumor-associated macrophages
3D cell culture models
macrophage reprogramming
cancer cell spheroids
chemokines
Online Access:https://www.mdpi.com/1422-0067/24/13/10763

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https://www.mdpi.com/1422-0067/24/13/10763

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