NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes

NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes

Summary: Thermogenic brown and beige adipocytes counteract obesity by enhancing energy dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these cells, a major source of disease susceptibility, has been less well studied. Here we examined beige adipocytes from ob...

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Bibliographic Details
Main Authors: Yuta Hiraike, Shuichi Tsutsumi, Takahito Wada, Misato Oguchi, Kaede Saito, Masahiro Nakamura, Satoshi Ota, Michinori Koebis, Harumi Nakao, Atsu Aiba, Gaku Nagano, Haruya Ohno, Kenji Oki, Masayasu Yoneda, Takashi Kadowaki, Hiroyuki Aburatani, Hironori Waki, Toshimasa Yamauchi
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Physiology
Molecular physiology
Molecular biology
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422201001X

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http://www.sciencedirect.com/science/article/pii/S258900422201001X

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