Repurposing of promoters and enhancers during mammalian evolution

Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...

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Bibliographic Details
Main Authors: Francesco N. Carelli, Angélica Liechti, Jean Halbert, Maria Warnefors, Henrik Kaessmann
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06544-z