Repurposing of promoters and enhancers during mammalian evolution
Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2018-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-06544-z |
| _version_ | 1819039807886589952 |
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| author | Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann |
| author_facet | Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann |
| author_sort | Francesco N. Carelli |
| collection | DOAJ |
| description | Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution. |
| first_indexed | 2024-12-21T08:59:05Z |
| format | Article |
| id | doaj.art-01df0f7d13964ee1b3ec70ae5ce9cc3a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T08:59:05Z |
| publishDate | 2018-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-01df0f7d13964ee1b3ec70ae5ce9cc3a2022-12-21T19:09:29ZengNature PortfolioNature Communications2041-17232018-10-019111110.1038/s41467-018-06544-zRepurposing of promoters and enhancers during mammalian evolutionFrancesco N. Carelli0Angélica Liechti1Jean Halbert2Maria Warnefors3Henrik Kaessmann4Center for Integrative Genomics, University of LausanneCenter for Integrative Genomics, University of LausanneCenter for Integrative Genomics, University of LausanneCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH AllianceCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH AllianceEnhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.https://doi.org/10.1038/s41467-018-06544-z |
| spellingShingle | Francesco N. Carelli Angélica Liechti Jean Halbert Maria Warnefors Henrik Kaessmann Repurposing of promoters and enhancers during mammalian evolution Nature Communications |
| title | Repurposing of promoters and enhancers during mammalian evolution |
| title_full | Repurposing of promoters and enhancers during mammalian evolution |
| title_fullStr | Repurposing of promoters and enhancers during mammalian evolution |
| title_full_unstemmed | Repurposing of promoters and enhancers during mammalian evolution |
| title_short | Repurposing of promoters and enhancers during mammalian evolution |
| title_sort | repurposing of promoters and enhancers during mammalian evolution |
| url | https://doi.org/10.1038/s41467-018-06544-z |
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