Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

Differentiation and dedifferentiation of vascular smooth muscle cells (VSMCs) are essential processes of vascular development. VSMCs have biosynthetic, proliferative and contractile roles in the vessel wall. Alterations in the differentiated state of the VSMCs play a critical role in the pathogenesi...

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Bibliographic Details
Main Authors: Mario eChiong, Benjamín eCartes-Saavedra, Ignacio eNorambuena-Soto, David eMondaca-Ruff, Pablo Esteban Morales, Marina eGarcía-Miguel, Rosemarie eMellado
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Endoplasmic Reticulum
proliferation
vascular smooth muscle cells
Mitofusin 2
mitochondria metabolism
mitochondria dynamics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00072/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00072/full

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